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  <xsd:element id="hstm_DebtInstrumentCovenantMaximumFundedDebtLeverageRatio" name="DebtInstrumentCovenantMaximumFundedDebtLeverageRatio" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_DocumentAndEntityInformation" name="DocumentAndEntityInformation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_EffectiveIncomeTaxRateReconciliationChangeInEstimatedTaxCreditsAmount" name="EffectiveIncomeTaxRateReconciliationChangeInEstimatedTaxCreditsAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_EffectiveIncomeTaxRateReconciliationChangeInFairValueOfNoncontrollingInterestAmount" name="EffectiveIncomeTaxRateReconciliationChangeInFairValueOfNoncontrollingInterestAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_ElectronicEducationDocumentationSystemLlcMember" name="ElectronicEducationDocumentationSystemLlcMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_FirstQuarterDividendsMember" name="FirstQuarterDividendsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_GainLossOnNonMarketableEquityInvestments" name="GainLossOnNonMarketableEquityInvestments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_IncomeTaxExpenseBenefitDiscreteAdjustments" name="IncomeTaxExpenseBenefitDiscreteAdjustments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_IncomeTaxExpenseBenefitMerger" name="IncomeTaxExpenseBenefitMerger" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_IncomeTaxExpenseBenefitStateAppointmentChange" name="IncomeTaxExpenseBenefitStateAppointmentChange" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_IncomeTaxExpenseBenefitStockbasedAwards" name="IncomeTaxExpenseBenefitStockbasedAwards" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_IncomeTaxExpenseNonTaxableGain" name="IncomeTaxExpenseNonTaxableGain" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element id="hstm_IncreaseDecreaseInDeferredCommissions" name="IncreaseDecreaseInDeferredCommissions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_LetterOfCreditSubfacilityMember" name="LetterOfCreditSubfacilityMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_LineOfCreditFacilityIncreasedFacilitySizeDueToAccordionFeature" name="LineOfCreditFacilityIncreasedFacilitySizeDueToAccordionFeature" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element id="hstm_LineOfCreditFacilityPercentageOfApplicableMarginForBorrowings" name="LineOfCreditFacilityPercentageOfApplicableMarginForBorrowings" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_NotBasedOn2023PerformanceMember" name="NotBasedOn2023PerformanceMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_NoteToFinancialStatementDetailsTextual" name="NoteToFinancialStatementDetailsTextual" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_NotesToFinancialStatements" name="NotesToFinancialStatements" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_NotesToFinancialStatementsAbstract" name="NotesToFinancialStatementsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_PerformanceBasedRestrictedStockUnitsRsusMember" name="PerformanceBasedRestrictedStockUnitsRsusMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_ProceedsFromTheSaleOfNonmarketableEquityInvestments" name="ProceedsFromTheSaleOfNonmarketableEquityInvestments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_ProductDevelopmentMember" name="ProductDevelopmentMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_ProfessionalServicesMember" name="ProfessionalServicesMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_ReserveForUncertainTaxPosition" name="ReserveForUncertainTaxPosition" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_SecondQuarterDividendsMember" name="SecondQuarterDividendsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_September2023ShareRepurchaseProgramMember" name="September2023ShareRepurchaseProgramMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncrementalPerformancePercentageYearFive" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardIncrementalPerformancePercentageYearFive" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncrementalPerformancePercentageYearFour" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardIncrementalPerformancePercentageYearFour" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncrementalPerformancePercentageYearThree" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardIncrementalPerformancePercentageYearThree" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_Sharebasedcompensationarrangementbysharebasedpaymentawardincrementalperformancepercentageyearone" name="Sharebasedcompensationarrangementbysharebasedpaymentawardincrementalperformancepercentageyearone" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_Sharebasedcompensationarrangementbysharebasedpaymentawardincrementalperformancepercentageyeartwo" name="Sharebasedcompensationarrangementbysharebasedpaymentawardincrementalperformancepercentageyeartwo" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration"/>
  <xsd:element id="hstm_StockRepurchasedAccruedExpense" name="StockRepurchasedAccruedExpense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant"/>
  <xsd:element id="hstm_StockRepurchasedAveragePricePerShare" name="StockRepurchasedAveragePricePerShare" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_SubscriptionServicesMember" name="SubscriptionServicesMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_SwingLineSubfacilityMember" name="SwingLineSubfacilityMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_ThirdAmendmentMember" name="ThirdAmendmentMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_ThirdQuarterDividendsMember" name="ThirdQuarterDividendsMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_TruistBankMember" name="TruistBankMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_TwoThousandTwentyThreePerformanceMember" name="TwoThousandTwentyThreePerformanceMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-2-revenue-recognition-and-sales-commissions-revenues-disaggregated-by-revenue-source-details" name="statement-statement-note-2-revenue-recognition-and-sales-commissions-revenues-disaggregated-by-revenue-source-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-2-revenue-recognition-and-sales-commissions-tables" name="statement-statement-note-2-revenue-recognition-and-sales-commissions-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-4-shareholders-equity-dividend-policy-details" name="statement-statement-note-4-shareholders-equity-dividend-policy-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-4-shareholders-equity-summary-of-stockbased-compensation-expense-details" name="statement-statement-note-4-shareholders-equity-summary-of-stockbased-compensation-expense-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-4-shareholders-equity-tables" name="statement-statement-note-4-shareholders-equity-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-5-earnings-per-share-computation-of-basic-and-diluted-earnings-per-share-details" name="statement-statement-note-5-earnings-per-share-computation-of-basic-and-diluted-earnings-per-share-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-5-earnings-per-share-tables" name="statement-statement-note-5-earnings-per-share-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-6-marketable-securities-fair-value-of-available-for-sale-marketable-securities-details" name="statement-statement-note-6-marketable-securities-fair-value-of-available-for-sale-marketable-securities-details" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
  <xsd:element abstract="true" id="hstm_statement-statement-note-6-marketable-securities-tables" name="statement-statement-note-6-marketable-securities-tables" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration"/>
</xsd:schema>
